Fig. 1 · Structure
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Sibrafiban
Glycoprotein IIb/IIIa Receptor Antagonist
Sibrafiban is a selective glycoprotein IIb/IIIa receptor antagonist that acts as an orally active, nonpeptide double proagent derived from Ro 44-3888. It effectively inhibits platelet aggregation, making it a valuable tool in the study of thrombotic diseases and platelet function. This compound is often utilized in research applications focused on cardiovascular health and the development of antithrombotic therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 172927-65-0 |
| Applications | Glycoprotein IIb/IIIa Receptor Antagonist |
| Formula | C20H28N4O6 |
| Molecular Weight | 420.47 |
| Synonyms | RO 48-3657 |
| SMILES | O=C(OCC)COC1CCN(C([C@@H](NC(C2=CC=C(/C(N)=N/O)C=C2)=O)C)=O)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.