Fig. 1 · Structure
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SIJ1777
Anticancer Agent
SIJ1777 is a potent anticancer agent targeting melanoma cells with BRAF class I/II/III mutations. It effectively inhibits the activation of key signaling pathways, including MEK, ERK, and AKT. SIJ1777 induces apoptosis and significantly reduces cell migration, invasion, and anchorage-independent growth, making it a valuable tool for research in cancer biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 839707-55-0 |
| Applications | Anticancer Agent |
| Formula | C26H23F3N8O2 |
| Molecular Weight | 536.51 |
| SMILES | O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=NN(C)C=C4)N=C3N(C)C2=O)=C1)C5=CC=CC(C(F)(F)F)=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.