Simvastatin Acyl-β-D-glucuronide is a primary metabolite of Simvastatin, which functions as a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. This compound plays a significant role in the pharmacokinetics of Simvastatin and is utilized in research applications focused on lipid metabolism and cholesterol regulation. Its analysis can provide insights into the metabolic pathways and efficacy of statin therapeutics.
Simvastatin Acyl-β-D-glucuronide is a primary metabolite of Simvastatin, which functions as a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. This compound plays a significant role in the pharmacokinetics of Simvastatin and is utilized in research applications focused on lipid metabolism and cholesterol regulation. Its analysis can provide insights into the metabolic pathways and efficacy of statin therapeutics.
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