Simvastatin-d11 is a deuterium-labeled analog of Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. This stable isotope is utilized in pharmacokinetic studies to trace drug metabolism and distribution in biological systems. Simvastatin-d11 not only aids in the investigation of cholesterol synthesis but also supports research on the therapeutic effects of statins in lipid regulation and cardiovascular disease.
Simvastatin-d11 is a deuterium-labeled analog of Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. This stable isotope is utilized in pharmacokinetic studies to trace drug metabolism and distribution in biological systems. Simvastatin-d11 not only aids in the investigation of cholesterol synthesis but also supports research on the therapeutic effects of statins in lipid regulation and cardiovascular disease.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
