Simvastatin-d3 is a deuterated analog of Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase, exhibiting a Ki of 0.2 nM. This stable isotope is useful for pharmacokinetic studies and metabolic tracing in lipid regulation research. Its specificity towards HMG-CoA reductase makes it an important tool for investigating cholesterol biosynthesis and the effects of statins on cellular metabolism.
Simvastatin-d3 is a deuterated analog of Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase, exhibiting a Ki of 0.2 nM. This stable isotope is useful for pharmacokinetic studies and metabolic tracing in lipid regulation research. Its specificity towards HMG-CoA reductase makes it an important tool for investigating cholesterol biosynthesis and the effects of statins on cellular metabolism.
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