Fig. 1 · Structure
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SIRT2-IN-9
SIRT2 Inhibitor
SIRT2-IN-9 is a selective inhibitor of SIRT2, exhibiting an IC50 value of 1.3 μM. This compound effectively inhibits the proliferative activity of MCF-7 breast cancer cells, highlighting its potential in cancer research. SIRT2-IN-9 serves as a valuable tool for investigating the role of SIRT2 in cancer biology and therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 522650-91-5 |
| Applications | SIRT2 Inhibitor |
| Formula | C21H22N6OS2 |
| Molecular Weight | 438.57 |
| SMILES | O=C(NC1=NC(CCCC2)=C2S1)CSC3=NN=C4C(N(CCC)C5=C4C=CC=C5)=N3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.