SIRT5 Inhibitor 4 is a selective inhibitor of the SIRT5 enzyme, demonstrating an IC50 value of 26.4 μM. This compound exhibits minimal activity against other SIRT subtypes, with an IC50 greater than 400 μM, underscoring its specificity. It serves as a valuable tool for investigating the biological roles of SIRT5 in metabolic regulation and related pathways. Research applications include studying SIRT5's involvement in cellular processes and potential therapeutic targets in metabolic disorders.
SIRT5 Inhibitor 4 is a selective inhibitor of the SIRT5 enzyme, demonstrating an IC50 value of 26.4 μM. This compound exhibits minimal activity against other SIRT subtypes, with an IC50 greater than 400 μM, underscoring its specificity. It serves as a valuable tool for investigating the biological roles of SIRT5 in metabolic regulation and related pathways. Research applications include studying SIRT5's involvement in cellular processes and potential therapeutic targets in metabolic disorders.
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