Sirtinol

Catalog No.: A12226
sirtuin inhibitor
Sirtinol is a cell-permeable, specific inhibitor of sirtuin NAD-dependant histone deacetylases. It is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM in cell-free assays, respectively.
Grouped product items
Product Name Price Stock Qty
Sirtinol 10mg
$80.00
In stock
Sirtinol 25mg
$170.00
In stock
Sirtinol 50mg
$300.00
In stock

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription Sirtinol is a cell-permeable, specific inhibitor of sirtuin NAD-dependant histone deacetylases. It is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM in cell-free assays, respectively.
Targets
Target Value
Chemical Information
Catalog Num A12226
Formula C26H22N2O2
Molecular Weight 394.47
CAS Number 410536-97-9
SMILES O=C(N([H])C(C1=CC=CC=C1)C)C(C=CC=C2)=C2/N=C/C3=C(O)C=CC4=C3C=CC=C4
Synonyms Sir Two Inhibitor Naphthol
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 20 mg/mL (50.7 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 0.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.75 mL 253.5 mL
0.5 mM 5.07 mL 25.35 mL 50.7 mL
1 mM 2.54 mL 12.68 mL 25.35 mL
5 mM 0.51 mL 2.54 mL 5.07 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy Sirtinol | Sirtinol Supplier | purchase Sirtinol | Sirtinol cost | Sirtinol manufacturer | order Sirtinol | Sirtinol distributor | buy 410536-97-9 | 410536-97-9 Supplier | purchase 410536-97-9 | 410536-97-9 cost | 410536-97-9 manufacturer | order 410536-97-9 | 410536-97-9 distributor