Sirtinol

Catalog No.: A12226

sirtuin inhibitor

Sirtinol

Sirtinol Chemical Structure

CAS NO. 410536-97-9

Sirtinol is a cell-permeable, specific inhibitor of sirtuin NAD-dependant histone deacetylases. It is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM in cell-free assays, respectively.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $80.00

Special Price $72.00

25 mg

Regular Price: $170.00

Special Price $153.00

50 mg

Regular Price: $300.00

Special Price $270.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Sirtinol is a cell-permeable, specific inhibitor of sirtuin NAD-dependant histone deacetylases. It is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM in cell-free assays, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.75 mL 253.5 mL
0.5 mM 5.07 mL 25.35 mL 50.7 mL
1 mM 2.54 mL 12.68 mL 25.35 mL
5 mM 0.51 mL 2.54 mL 5.07 mL

*The above data is based on the productmolecular weight 394.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12226
Actions Inhibitor
M. Wt 394.47
Formula C26H22N2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 410536-97-9
Synonyms Sir Two Inhibitor Naphthol
SMILES O=C(N([H])C(C1=CC=CC=C1)C)C(C=CC=C2)=C2/N=C/C3=C(O)C=CC4=C3C=CC=C4

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