SIS-17

Catalog No.: A18463

HDAC 11 inhibitor

SIS-17

SIS-17 Chemical Structure

CAS NO. 2374313-54-7

SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$120.00
50 mg
$350.00
100 mg
$620.00
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Biological Activity

SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.28 mL 136.39 mL 272.78 mL
0.5 mM 5.46 mL 27.28 mL 54.56 mL
1 mM 2.73 mL 13.64 mL 27.28 mL
5 mM 0.55 mL 2.73 mL 5.46 mL

*The above data is based on the productmolecular weight 366.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18463
Actions Inhibitor
M. Wt 366.6
Formula C21H38N2OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2374313-54-7
Synonyms SIS-17; SIS 17; SIS17;
SMILES O=C(C1=CC=CS1)NNCCCCCCCCCCCCCCCC

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