Signaling Pathway
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| Discription | SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs. | ||
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| Targets |
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| Catalog Num | A18463 |
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| Formula | C21H38N2OS |
| Molecular Weight | 366.6 |
| CAS Number | 2374313-54-7 |
| SMILES | O=C(C1=CC=CS1)NNCCCCCCCCCCCCCCCC |
| Synonyms | SIS-17; SIS 17; SIS17; |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 68 mg/mL (185.48 mM) | |
| Water | Insoluble | ||
| Ethanol | 17 mg/mL (46.36 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.28 mL | 136.39 mL | 272.78 mL |
| 0.5 mM | 5.46 mL | 27.28 mL | 54.56 mL |
| 1 mM | 2.73 mL | 13.64 mL | 27.28 mL |
| 5 mM | 0.55 mL | 2.73 mL | 5.46 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
