Fig. 1 · Structure

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(–)-Sitagliptin carbamoyl glucuronide

Dipeptidyl Peptidase Control

(–)-Sitagliptin carbamoyl glucuronide is a minor metabolite of the Dipeptidyl Peptidase 4 (DPP-4) inhibitor, Sitagliptin. It serves as a valuable reference compound for the study of DPP-4 activity and inhibition. This metabolite can be used in pharmacokinetic studies and helps in understanding the metabolism and efficacy of DPP-4 inhibitors in therapeutic applications, particularly in diabetes research.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 940002-59-5
Applications Dipeptidyl Peptidase Control
Formula C23H23F6N5O9
Molecular Weight 627.45
SMILES
O=C([C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC(N[C@@H](CC(N2CC3=NN=C(C(F)(F)F)N3CC2)=O)CC4=CC(F)=C(F)C=C4F)=O)O1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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