Fig. 1 · Structure
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SJ000063181
BMP Signaling Activator
SJ000063181 is a potent BMP signaling activator that specifically enhances the activity of bone morphogenetic protein 4 (BMP4) and promotes the phosphorylation of SMAD1/5/8 (p-SMAD1/5/8). This compound is utilized in research to investigate BMP pathway modulation and its effects on developmental processes. In vivo studies have demonstrated that SJ000063181 induces ventralization in zebrafish embryos, making it a valuable tool for developmental biology and embryonic research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 945189-68-4 |
| Applications | BMP Signaling Activator |
| Formula | C14H14ClFN2O2 |
| Molecular Weight | 296.72 |
| SMILES | CC(CC1=CC(C(NC2=CC(Cl)=C(F)C=C2)=O)=NO1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.