SJ46411 is a potent ligand for KLHDC2, demonstrating a binding affinity with a Kd of approximately 260 nM as determined by isothermal titration calorimetry. Additional characterization includes SPR Kd of 0.5 μM and a TR-FRET IC50 of 3.9 μM, alongside a notable increase in thermal stability indicated by a ΔTm of 6.0 °C. This compound is valuable for research involving KLHDC2 interactions and can aid in elucidating its biological roles and potential as a therapeutic target.
SJ46411 is a potent ligand for KLHDC2, demonstrating a binding affinity with a Kd of approximately 260 nM as determined by isothermal titration calorimetry. Additional characterization includes SPR Kd of 0.5 μM and a TR-FRET IC50 of 3.9 μM, alongside a notable increase in thermal stability indicated by a ΔTm of 6.0 °C. This compound is valuable for research involving KLHDC2 interactions and can aid in elucidating its biological roles and potential as a therapeutic target.
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