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SJ46411

KLHDC2 Ligand

SJ46411 is a potent ligand for KLHDC2, demonstrating a binding affinity with a Kd of approximately 260 nM as determined by isothermal titration calorimetry. Additional characterization includes SPR Kd of 0.5 μM and a TR-FRET IC50 of 3.9 μM, alongside a notable increase in thermal stability indicated by a ΔTm of 6.0 °C. This compound is valuable for research involving KLHDC2 interactions and can aid in elucidating its biological roles and potential as a therapeutic target.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3086104-39-1
Applications	KLHDC2 Ligand
Formula	C₁₇H₁₄N₂O₃S
Molecular Weight	326.37
SMILES	O=C(CNC(CC1=CSC(C2=CC=C3C=CC=CC3=C2)=N1)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.