Fig. 1 · Structure

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SJPYT-195

GSPT1 Degrader

SJPYT-195 is a potent GSPT1 degrader that functions through targeted protein degradation mechanisms. This compound induces proteolysis of GSPT1, leading to cytotoxic effects in various cell types. It is a valuable tool for research applications focused on studying GSPT1-related pathways and for the synthesis of PROTACs (Proteolysis Targeting Chimeras) designed to selectively degrade proteins of interest.

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Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 2973762-16-0
Applications GSPT1 Degrader
Formula C35H34N6O8
Molecular Weight 666.68
SMILES
O=C(C1=C(C)N(C2=CC(OC)=CC=C2OC)N=N1)NC3=CC(OC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=CC(C(C)(C)C)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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