Fig. 1 · Structure

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SJPYT-328

PXR Agonist

SJPYT-328 is a potent agonist of the Pregnane X Receptor (PXR), which is crucial for regulating drug metabolism and influencing drug-drug interactions. Its activation of PXR can significantly impact the transcription of various cytochrome P450 enzymes, thereby modulating the pharmacokinetics of co-administered drugs. This compound is valuable for research applications focused on pharmacology, toxicology, and the study of metabolic pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 2998548-72-2
Applications PXR Agonist
Formula C29H40N4O4
Molecular Weight 508.65
SMILES
COC1=C(N2C(C)=C(N=N2)C(NC3=C(C=CC(C(C)(C)C)=C3)O[C@@H](CC)CCC)=O)C=C(C(OC)=C1)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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