Fig. 1 · Structure

Documents & Downloads

SK-575

PARP1 Degrader

SK-575 is a highly potent and selective PROTAC degrader of PARP1, with an IC₅₀ of 2.30 nM. It effectively inhibits the proliferation of cancer cells harboring BRCA1/2 mutations, making it a valuable agent for targeted cancer research.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 2523016-96-6
Applications PARP1 Degrader
Formula C47H53FN8O8
Molecular Weight 876.97
SMILES
O=C(NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CCCCCCCCCCC(N4CCN(C(C5=CC(CC6=NNC(C7=C6C=CC=C7)=O)=CC=C5F)=O)CC4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Added to your cart

View Cart Checkout
Loading...