Fig. 1 · Structure
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SK609
Dopamine Receptor
SK609 is a selective agonist of the dopamine D3 receptor, enhancing dopamine and norepinephrine levels in the cerebral cortex. This compound has demonstrated efficacy in suppressing dyskinesias in preclinical models of Parkinson's disease and alleviating muscle twitches caused by L-dopa treatment. Additionally, SK609 has been shown to improve performance in sustained attention tasks by significantly reducing both misses and false alarms. Research indicates that SK609 may offer therapeutic potential for mitigating movement and cognitive deficits associated with Parkinson's disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 144887-95-6 |
| Applications | Dopamine Receptor |
| Formula | C10H14ClN |
| Molecular Weight | 183.68 |
| SMILES | ClC1=C(CCC(C)N)C=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.