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SKF 10810

GABAA Receptor Antagonist

SKF 10810 is a GABAA receptor antagonist with an EC50 of 4.3 μM, demonstrating a notable capacity to inhibit GABAergic signaling. By disrupting GABA-mediated inhibition in reward pathways of the brain, SKF 10810 may have potential antidepressant effects. This compound serves as a valuable tool for research into neurological disorders and the mechanisms underlying mood regulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	22196-65-2
Applications	GABAA Receptor Antagonist
Formula	C₁₉H₂₀F₃NO
Molecular Weight	335.36
SMILES	FC(C1=CC(C(CCCN(C)C)C2=C(C=CC=C2)O3)=C3C=C1)(F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.