Fig. 1 · Structure

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SKF 83509

Dopamine D1 Antagonist

SKF 83509 is a selective dopamine D1 antagonist with a Ki value of 70.2 nM, demonstrating no activity at dopamine D2 receptors. This compound is primarily utilized in neuropharmacological research to investigate the role of dopamine D1 receptors in various neurological conditions. SKF 83509 aids in the exploration of dopaminergic signaling pathways and contributes to studies focused on drug addiction, schizophrenia, and other dopamine-related disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 90955-43-4
Applications Dopamine D1 Antagonist
Formula C16H17BrClNO
Molecular Weight 354.67
SMILES
OC1=C(Cl)C=C2CCNCC(C3=CC=CC=C3)C2=C1.Br

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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