SKI-178

Name: SKI-178
Brand: Adooq Bioscience
SKU: A22510
Rating: 5 (288 reviews)

Catalog No.: A22510

SphK1 inhibitor

SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor (IC50 = 0.1-1.8 μM). Induces CDK1-dependent apoptosis in human acute myeloid leukemia cell lines. Active in vivo.

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Grouped product items
Size	Price	Stock
2mg	$35.00	In stock
5mg	$55.00	In stock
10mg	$95.00	In stock
25mg	$220.00	In stock
50mg	$355.00	In stock
100mg	$540.00	In stock
500mg	$1,165.00	In stock
*10mM 1mL in DMSO**	$65.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description

SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor (IC50 = 0.1-1.8 μM). Induces CDK1-dependent apoptosis in human acute myeloid leukemia cell lines. Active in vivo.

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A22510
Formula	C21H22N4O4
Molecular Weight	394.431
CAS Number	1259484-97-3
SMILES	O=C(C1=CC(C2=CC=C(OC)C=C2)=NN1)N/N=C(C3=CC=C(OC)C(OC)=C3)\C
Synonyms	SKI-178, SKI 178, SKI178.
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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