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- Massimo Costanza, .et al. DNA threads released by activated CD4+ T lymphocytes provide autocrine costimulation, PNAS, 2019, 2019
Biological Activity
SKQ1 is a potent mitochondria-targeted antioxidant. SKQ1 is also an API (active pharmaceutical ingredient) for making eye drop drug called Visomitin. SKQ1 showed activities (1) to prevent amyloid-beta-induced impairment of long-term potentiation in rat hippocampal slices.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.19 mL | 80.96 mL | 161.92 mL |
| 0.5 mM | 3.24 mL | 16.19 mL | 32.38 mL |
| 1 mM | 1.62 mL | 8.1 mL | 16.19 mL |
| 5 mM | 0.32 mL | 1.62 mL | 3.24 mL |
*The above data is based on the productmolecular weight 617.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15464 |
|---|---|
| CAS No. | 934826-68-3 |
| Formula | C36H42BrO2P |
| M. Wt | 617.6 |
| Purity | >98% |
| Synonyms | PDTP |
| SMILES | O=C(C(CCCCCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=C4)C(C)=C(C)C4=O.[Br-] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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