Fig. 1 · Structure
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SL651498
Anxiolytic Agent
SL651498 is a full agonist of α2 and α3 GABAA receptors, with partial agonist activity at α1 and α5 GABAA receptors. This compound demonstrates significant anxiolytic and anticonvulsant properties, making it a valuable tool in research focused on anxiety disorders and seizure management. Its selective receptor modulation provides a useful model for investigating therapeutic interventions targeting GABAA receptor subtypes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 205881-86-3 |
| Applications | Anxiolytic Agent |
| Formula | C23H20FN3O2 |
| Molecular Weight | 389.42 |
| SMILES | O=C(C1=CN(C(C2=C1C3=C(C=CC(F)=C3)N2C)=O)C4=CC=CC=C4)N5CCCC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.