Fig. 1 · Structure
Documents & Downloads
SLC13A5-IN-1
SLC3A5 Inhibitor
SLC13A5-IN-1 is a selective inhibitor of the sodium-citrate co-transporter SLC13A5. It effectively blocks the uptake of 14C-citrate in HepG2 cells with an IC50 of 0.022 μM, demonstrating its potency. This compound holds promise for research applications related to the treatment of metabolic and cardiovascular diseases, providing a valuable tool for investigating the physiological role of citrate transport. SLC13A5-IN-1 is derived from patent WO2018104220A1, Compound I-5.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2227548-95-8 |
| Applications | SLC3A5 Inhibitor |
| Formula | C19H19Cl3N2O3S |
| Molecular Weight | 461.79 |
| SMILES | O=C(C1CCN(S(=O)(C2=CC(Cl)=CC(Cl)=C2)=O)CC1)NCC3=CC=C(Cl)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.