Fig. 1 · Structure
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SLEC-11
Synthetic Lethal Lead
SLEC-11 is a synthetic lethal lead that acts as a modulator of CDH1/E-cadherin. It effectively inhibits cell death in E-cadherin-deficient cells, with an EC50 value of 8.2 μM. This compound is valuable for investigating potential synthetic lethal therapies in the context of gastric cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 863761-17-5 |
| Applications | Synthetic Lethal Lead |
| Formula | C18H17FN2O |
| Molecular Weight | 296.34 |
| SMILES | FC1=CC=C(CNC2=CC(C)=NC3=C2C=C(OC)C=C3)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.