SLV-2436

Catalog No.: A20294
MNK1 and MNK2 inhibitor
SLV-2436 is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50s of 10.8 ?nM and 5.4 nM, respectively.
Grouped product items
Product Name Price Stock Qty
SLV-2436 5mg
$198.00
In stock
SLV-2436 10mg
$341.00
In stock
SLV-2436 50mg
$1,012.00
In stock
SLV-2436 100mg
$2,024.00
In stock
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Biological Activity
Discription SLV-2436 is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50s of 10.8 ?nM and 5.4 nM, respectively.
Targets
Target Value
Product Information
Catalog Num A20294
Formula C19H15ClN4O
Molecular Weight 350.8
CAS Number 2095704-43-9
SMILES O=C1C=CC(C2=CC3=C(C=C2)C(N)=NN3)=CN1CC4=CC=CC(Cl)=C4
Synonyms SLV2436, SLV 2436, SEL201-88, SEL-201-88, SEL 201-88; SEL-201, SEL201, SEL 201
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 66 mg/mL (188.14 mM)
Water Insoluble
Ethanol 5 mg/mL (14.25 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.51 mL 142.53 mL 285.06 mL
0.5 mM 5.7 mL 28.51 mL 57.01 mL
1 mM 2.85 mL 14.25 mL 28.51 mL
5 mM 0.57 mL 2.85 mL 5.7 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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