SLx-2119 (KD025)

Catalog No.: A15239

ROCK2 Inhibitor

SLx-2119 (KD025)

SLx-2119 (KD025) Chemical Structure

CAS NO. 911417-87-3

SLx-2119 is a small molecule and selective inhibitor of ROCK2 with IC50 of 105 nM; > 200 fold selecivity over ROCK1(IC50 =24 uM).

Availability: In stock

Package Price Qty
5 mg

Regular Price: $70.00

Special Price $56.00

10 mg

Regular Price: $95.00

Special Price $76.00

100 mg

Regular Price: $490.00

Special Price $392.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

SLx-2119 is a small molecule and selective inhibitor of ROCK2 with IC50 of 105 nM; > 200 fold selecivity over ROCK1(IC50 =24 uM).
Targets
ROCK2 ROCK2
41 nM(Ki)60 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.1 mL 110.49 mL 220.99 mL
0.5 mM 4.42 mL 22.1 mL 44.2 mL
1 mM 2.21 mL 11.05 mL 22.1 mL
5 mM 0.44 mL 2.21 mL 4.42 mL

*The above data is based on the productmolecular weight 452.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A15239
Actions Inhibitor
M. Wt 452.51
Formula C26H24N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 911417-87-3
Synonyms SLx 2119, SLx2119, ROCK inhibitor, KD-025
SMILES CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC3=CC=CC=C3C(=N2)NC4=CC5=C(C=C4)NN=C5

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