SLx-2119 (KD025)

Catalog No.: A15239
ROCK2 Inhibitor
SLx-2119 is a small molecule and selective inhibitor of ROCK2 with IC50 of 105 nM; > 200 fold selecivity over ROCK1(IC50 =24 uM).
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SLx-2119 5mg
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SLx-2119 10mg
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SLx-2119 100mg
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Biological Activity
Discription SLx-2119 is a small molecule and selective inhibitor of ROCK2 with IC50 of 105 nM; > 200 fold selecivity over ROCK1(IC50 =24 uM).
Target Value
Product Information
Catalog Num A15239
Formula C26H24N6O2
Molecular Weight 452.51
CAS Number 911417-87-3
Synonyms SLx 2119, SLx2119, ROCK inhibitor, KD-025

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO 84 mg/mL (185.63 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+35% PEG 300+2%Tween 80+ddH2O 6 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.1 mL 110.49 mL 220.99 mL
0.5 mM 4.42 mL 22.1 mL 44.2 mL
1 mM 2.21 mL 11.05 mL 22.1 mL
5 mM 0.44 mL 2.21 mL 4.42 mL
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