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SM-122

Smac Mimetic

SM-122 is a monovalent Smac mimetic that targets cellular inhibitors of apoptosis proteins cIAP-1 and cIAP-2. By promoting the degradation of cIAP-1/2, SM-122 can induce apoptosis in tumor cells. This compound is valuable for research applications related to cancer, including studies focusing on breast cancer.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	874270-38-9
Applications	Smac Mimetic
Formula	C₂₈H₃₆N₄O₃
Molecular Weight	476.61
SMILES	O=C([C@H]1N2[C@](CCCC[C@@H](C2=O)NC([C@H](C)NC)=O)([H])CC1)NC(C3=CC=CC=C3)C4=CC=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.