Fig. 1 · Structure
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SM27
FGF Inhibitor
SM27 (NSC 37204) is a specific inhibitor of fibroblast growth factors (FGF). It disrupts the formation of the FGF2/heparan sulfate proteoglycans/FGFR1 complex, thereby inhibiting angiogenesis. This compound is primarily utilized in research applications focused on understanding the role of FGF signaling in cancer progression and vascular biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 6266-54-2 |
| Applications | FGF Inhibitor |
| Formula | C21H16N2O9S2 |
| Molecular Weight | 504.49 |
| Synonyms | NSC 37204 |
| SMILES | O=S(C1=CC(O)=C2C=C(C=CC2=C1)NC(NC3=CC=C4C=C(C=C(C4=C3)O)S(=O)(O)=O)=O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.