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SM45a

Targeting Ligand

SM45a is a small molecule targeting ligand designed to enhance the cellular uptake of RNA interference (RNAi) agents. It can be covalently linked to the 3' or 5' end of either a sense or antisense strand of DUX4 RNAi constructs, facilitating their entry into target cells. This compound is instrumental in research applications focused on gene silencing and therapeutics involving DUX4-related pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2764770-56-9
Applications	Targeting Ligand
Formula	C₃₂H₃₄N₄O₄
Molecular Weight	538.64
SMILES	CC1=CC=NC(NCCCCC(NCC(N[C@H](C2=CC=C(C=C2)C3=CC=CC4=C3C=CC=C4)CC(O)=O)=O)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.