Fig. 1 · Structure

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SM51a

Targeting Ligand

SM51a is a small molecule targeting ligand that facilitates cellular uptake of RNA interference agents. By conjugating SM51a to the 3' or 5' end of either a sense or antisense strand of a DUX4 RNAi agent, it enhances the delivery efficiency into cells. This functionality makes SM51a a valuable tool in gene silencing research and therapeutic applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2764770-62-7
Applications Targeting Ligand
Formula C31H32N4O4
Molecular Weight 524.61
SMILES
CC1=CC=NC(NCCCC(NCC(N[C@H](C2=CC=C(C=C2)C3=CC=CC4=C3C=CC=C4)CC(O)=O)=O)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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