Fig. 1 · Structure

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SMARCA2 ligand-10

target protein ligand

SMARCA2 ligand-10 is a specific ligand for the SMARCA2 protein, facilitating the development of targeted protein degradation techniques. This compound is utilized in the synthesis of PROTAC SMARCA2 degrader-28, enabling selective modulation of SMARCA2 activity. Its application is valuable for research into cancer biology and therapeutic strategies that involve targeted degradation of oncogenic proteins.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 3024271-84-6
Applications target protein ligand
Formula C16H18FN5O
Molecular Weight 315.35
SMILES
OC1=C(C2=CC(N3CC4NC(CC4)C3)=C(N)N=N2)C=C(F)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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