Fig. 1 · Structure

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SMARCA2 ligand-12

Ligand for Target Protein for PROTAC

SMARCA2 ligand-12 is a PROTAC target protein ligand designed for targeted protein degradation applications. This compound facilitates the synthesis of PROTAC SMARCA2 degrader-25, enabling the selective modulation of SMARCA2 protein levels. Its utility in research allows for the exploration of protein function and potential therapeutic interventions in associated diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 2755762-94-6
Applications Ligand for Target Protein for PROTAC
Formula C21H26N6O2
Molecular Weight 394.47
SMILES
O=C(C1CCNCC1)N2C[C@@]3([H])N(CC2)C4=CC(C5=C(C=CC=C5)O)=NN=C4NC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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