Fig. 1 · Structure
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SMARCA2 ligand-9
Ligand for Target Protein for PROTAC
SMARCA2 ligand-9 is a selective ligand for the target protein SMARCA2, designed for use in proteolysis-targeting chimera (PROTAC) applications. This compound facilitates the synthesis of PROTAC SMARCA2 degrader-27, enabling targeted degradation of SMARCA2 in cellular studies. Researchers can utilize SMARCA2 ligand-9 to investigate the role of SMARCA2 in various biological processes and assess its potential as a therapeutic target in cancer research and other diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 1997320-33-8 |
| Applications | Ligand for Target Protein for PROTAC |
| Formula | C21H21FN6O |
| Molecular Weight | 392.43 |
| SMILES | NC(N=N1)=C(N2CC3N(C4=CC(F)=NC=C4)C(CC3)C2)C=C1C5=CC=CC=C5O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.