Fig. 1 · Structure
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SMI-1074
Ligand for Target Protein for PROTAC
SMI-1074 is a ligand for target proteins in the development of PROTACs (Proteolysis Targeting Chimeras). It facilitates the targeted degradation of specific proteins, making it a valuable tool in research areas such as cancer biology and cellular regulation. SMI-1074 is also instrumental in the synthesis of related compounds SMD-3236 and SMD-1087, expanding its utility in chemical biology studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 3033592-13-8 |
| Applications | Ligand for Target Protein for PROTAC |
| Formula | C25H26ClN3O |
| Molecular Weight | 419.95 |
| SMILES | ClC1=CC=CC(N2C(C3(C4=C2C=C(C=C4)C5CCNCC5)CCCCC3)=N6)=C1C6=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.