Fig. 1 · Structure
Documents & Downloads
SMN-C2
SMN2 Splicing Regulator
SMN-C2 is a selective modulator of SMN2 gene splicing, functioning by binding to SMN2 pre-mRNA. This binding enhances the interaction of far upstream element binding protein 1 (FUBP1) and KH-spliced RNA binding protein (KHSRP) with the pre-mRNA complex. SMN-C2 is primarily utilized in research focused on spinal muscular atrophy (SMA), providing insights into therapeutic avenues for this condition.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1446311-56-3 |
| Applications | SMN2 Splicing Regulator |
| Formula | C24H27N5O2 |
| Molecular Weight | 417.50 |
| SMILES | O=C1C(C2=CN3C(C(C)=NC(C)=C3)=N2)=CC4=CC=C(N5C[C@H](C)N(CC)CC5)C=C4O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.