Fig. 1 · Structure
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SN-38-CO-DMEDA TFA
ADC Intermedia
SN-38-CO-DMEDA TFA serves as a crucial intermediate for the synthesis of antibody-drug conjugate LND1035. This compound facilitates targeted delivery of cytotoxic agents, enhancing therapeutic efficacy while minimizing systemic toxicity. Its role in the development of antibody-conjugated drugs makes it a valuable reagent for cancer research and drug development applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1224601-17-5 |
| Applications | ADC Intermedia |
| Formula | C29H31F3N4O8 |
| Molecular Weight | 620.57 |
| SMILES | CCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC=C(OC(N(C)CCNC)=O)C=C51.O=C(O)C(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.