Fig. 1 · Structure
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SNC80
δ-opioid Receptor Agonist
SNC80 is a highly selective and potent non-peptide δ-opioid receptor agonist, demonstrating a Ki of 1.78 nM and an IC50 of 2.73 nM. This compound selectively activates the μ-δ heteromer in HEK293 cells, exhibiting an EC50 of 52.8 nM. SNC80 is characterized by its antinociceptive, antihyperalgesic, and antidepressant-like activities, making it a valuable tool for research in the treatment of various headache disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 156727-74-1 |
| Applications | δ-opioid Receptor Agonist |
| Formula | C28H39N3O2 |
| Molecular Weight | 449.63 |
| Synonyms | NIH 10815 |
| SMILES | O=C(N(CC)CC)C1=CC=C([C@@H](N2[C@@H](C)CN(CC=C)[C@H](C)C2)C3=CC=CC(OC)=C3)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.