SNC80 is a highly selective and potent non-peptide δ-opioid receptor agonist, demonstrating a Ki of 1.78 nM and an IC50 of 2.73 nM. This compound selectively activates the μ-δ heteromer in HEK293 cells, exhibiting an EC50 of 52.8 nM. SNC80 is characterized by its antinociceptive, antihyperalgesic, and antidepressant-like activities, making it a valuable tool for research in the treatment of various headache disorders.
SNC80 is a highly selective and potent non-peptide δ-opioid receptor agonist, demonstrating a Ki of 1.78 nM and an IC50 of 2.73 nM. This compound selectively activates the μ-δ heteromer in HEK293 cells, exhibiting an EC50 of 52.8 nM. SNC80 is characterized by its antinociceptive, antihyperalgesic, and antidepressant-like activities, making it a valuable tool for research in the treatment of various headache disorders.
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