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SNS-032 (BMS-387032)


CDK inhibitor

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Catalog No. A10850

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SNS-032 5mg A10850-5

Regular Price: $40.00

Special Price: $36.00

SNS-032 10mg A10850-10

Regular Price: $60.00

Special Price: $54.00

SNS-032 50mg A10850-50

Regular Price: $180.00

Special Price: $162.00

SNS-032 100mg A10850-100

Regular Price: $300.00

Special Price: $270.00

SNS-032 (BMS-387032) 10mM * 1mL in DMSO A10850-10mM-D

Regular Price: $89.00

Special Price: $80.10

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SNS-032 (BMS-387032) is a highly selective and potent inhibitor of cyclin-dependent kinases (Cdks) 2, 7, and 9, with in vitro growth inhibitory effects and ability to induce apoptosis in malignant B cells.

SNS-032 (BMS-387032)

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Chemical Information

Catalog Num A10850
Actions Inhibitor
M. Wt 380.5
Formula C17H24N4O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 345627-80-7
Synonyms SNS032, BMS-387032, BMS387032

Biological Activity

SNS-032 (BMS-387032) is a highly selective and potent inhibitor of cyclin-dependent kinases (Cdks) 2, 7, and 9, with in vitro growth inhibitory effects and ability to induce apoptosis in malignant B cells.
Target Value
CDK9/CyclinTIC50: 4nM
CDK2/CyclinAIC50: 38nM
CDK2/CyclinEIC50: 48nM
CDK7/CyclinHIC50: 62nM
GSK-3αIC50: 230nM
CDK5/p35IC50: 340nM
CDK1/CyclinBIC50: 480nM
GSK-3βIC50: 660nM
CDK4/CyclinDIC50: 925nM
CDK6/CyclinDIC50: >1μM


Solubility (25°C) * In vitro DMSO 76 mg/mL (199.72 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.28 mL 131.41 mL 262.81mL
0.5 mM 5.26 mL 26.28 mL 52.56 mL
1 mM 2.63 mL 13.14 mL 26.28 mL
5 mM 0.53 mL 2.63 mL 5.26 mL

*The above data is based on the productmolecular weight 380.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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