Fig. 1 · Structure
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SNT-207858 free base
Melanocortin Receptor Antagonist
SNT-207858 free base is a selective melanocortin-4 (MC-4) receptor antagonist that effectively penetrates the blood-brain barrier. With an IC50 of 22 nM for binding and 11 nM for functional inhibition, this compound demonstrates potent activity against the MC-4 receptor. It is a valuable tool for research applications focused on understanding melanocortin signaling pathways and their implications in neurological and metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1104662-66-9 |
| Applications | Melanocortin Receptor Antagonist |
| Formula | C32H43Cl2N5O3 |
| Molecular Weight | 616.62 |
| SMILES | O=C(N1CCCC1)N[C@H](CC2=CC=C(Cl)C=C2Cl)C(N3CCC(C4=NC=CC=C4OC[C@H](N5CCCC5)CC)CC3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.