Fig. 1 · Structure
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SNX-482
CaV2.3 Channel Blocker
SNX-482 is a high-affinity, selective, and voltage-dependent blocker of the R-type calcium channel CaV2.3, exhibiting an IC50 of 30 nM. This peptide has demonstrated significant antinociceptive properties, making it a valuable reagent for research focused on pain mechanisms and calcium signaling pathways. Its specificity for CaV2.3 channels positions SNX-482 as a useful tool in studies related to neurology and pharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Blocker |
| CAS Number | 203460-30-4 |
| Applications | CaV2.3 Channel Blocker |
| Formula | C192H274N52O60S7 |
| Molecular Weight | 4495.00 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.