Fig. 1 · Structure
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SOD1-Derlin-1 inhibitor-1
SOD1-Derlin-1 Inhibitor
SOD1-Derlin-1 inhibitor-1 is a specific inhibitor of the SOD1-Derlin-1 interaction, displaying an IC50 value of 7.11 μM against the SOD1G93A-Derlin-1 complex. This compound is especially relevant for studies exploring mechanisms of amyotrophic lateral sclerosis (ALS) and potential therapeutic interventions. Its ability to disrupt the SOD1-Derlin-1 complex makes it a valuable tool for investigating the role of this interaction in neurodegenerative diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 840461-03-2 |
| Applications | SOD1-Derlin-1 Inhibitor |
| Formula | C19H12Br2N4OS |
| Molecular Weight | 504.20 |
| SMILES | NC(C1=CC=C(C2=CN=CC=C2)N=C1S3)=C3C(NC(C=CC(Br)=C4)=C4Br)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.