Fig. 1 · Structure
Documents & Downloads
Sofinicline benzenesulfonate
nAChR Agonist
Sofinicline benzenesulfonate is a potent agonist of the nicotinic acetylcholine receptor, specifically targeting the α4β2 subtype with an IC50 of 0.1 nM. This compound has demonstrated potential to enhance cognitive functions, including attention and memory, making it a valuable tool in the investigation of cognitive impairments. Its applications extend to research on attention deficit hyperactivity disorder (ADHD) and other cognitive disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 876170-44-4 |
| Applications | nAChR Agonist |
| Formula | C16H17Cl2N3O3S |
| Molecular Weight | 402.30 |
| Synonyms | ABT 894 benzenesulfonate |
| SMILES | O=S(O)(C1=CC=CC=C1)=O.ClC2=CC(N3C[C@@]4([H])[C@@](NC4)([H])C3)=CN=C2Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.