Fig. 1 · Structure
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Solanidine
Anticancer Agent
Solanidine is an orally active cholestane alkaloid that serves as an anticancer agent. Isolated from potato, Solanidine has been shown to decrease RAD51 levels while increasing γH2AX and p53 expression. This compound exhibits anti-tumor effects in LLC tumors and lung cancer models, while also promoting breast cancer cell proliferation. Additionally, Solanidine reduces neovascularization and has been associated with reproductive effects in certain animal models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 80-78-4 |
| Applications | Anticancer Agent |
| Formula | C27H43NO |
| Molecular Weight | 397.64 |
| SMILES | [H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@@]5([H])[C@H](C)[C@@]6([H])CC[C@H](C)CN6[C@]([H])5C[C@@]24[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.