Fig. 1 · Structure
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Soluble epoxide hydrolase inhibitor
Epoxide Hydrolase Inhibitor
Soluble epoxide hydrolase inhibitor targets soluble epoxide hydrolase (sEH) and demonstrates potent inhibition of human soluble epoxide hydrolase (h-sEH) with a pIC50 of 8.4. This compound plays a critical role in modulating the levels of epoxyeicosatrienoic acids (EETs) and is valuable in research applications related to cardiovascular and inflammatory diseases. Its inhibition can enhance cannabinoid signaling pathways, making it a useful tool for studying the effects of eicosanoids in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1241826-88-9 |
| Applications | Epoxide Hydrolase Inhibitor |
| Formula | C18H12F5N5O3 |
| Molecular Weight | 441.31 |
| SMILES | O=C(C1=CN2C(C=C1)=NN(CC(F)F)C2=O)NCC3=CC=C(C#N)C=C3OC(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.