Fig. 1 · Structure
Documents & Downloads
Sonrotoclax
Bcl2 Inhibitor
Sonrotoclax is a potent, orally bioavailable inhibitor of the Bcl-2 protein, which plays a crucial role in apoptosis regulation. This compound exhibits significant cytotoxic effects against various lymphoma and leukemia cell lines, making it a valuable tool for cancer research. Its ability to disrupt Bcl-2-mediated survival signals provides a basis for investigating therapeutic strategies in hematological malignancies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2383086-06-2 |
| Applications | Bcl2 Inhibitor |
| Formula | C49H59N7O7S |
| Molecular Weight | 890.10 |
| Synonyms | BGB 11417 |
| SMILES | CC(C1=C(C=CC=C1)[C@H]2N(CCC2)C3CC4(CCN(C5=CC(OC6=CN=C(NC=C7)C7=C6)=C(C=C5)C(NS(=O)(C8=CC([N+]([O-])=O)=C(C=C8)NC[C@@H]9CC[C@@](O)(CC9)C)=O)=O)CC4)C3)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.