Sonvuterkib

Catalog No.: A36755
ERK Inhibitor
Sonvuterkib is a potent inhibitor of extracellular signal-regulated kinases (ERK), demonstrating IC50 values of 1.4 nM for ERK1 and 0.54 nM for ERK2. This orally active compound effectively inhibits cell proliferation, making it a valuable tool in cancer research. Its ability to target ERK signaling pathways highlights its potential for therapeutic applications in various cancer models.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSonvuterkib is a potent inhibitor of extracellular signal-regulated kinases (ERK), demonstrating IC50 values of 1.4 nM for ERK1 and 0.54 nM for ERK2. This orally active compound effectively inhibits cell proliferation, making it a valuable tool in cancer research. Its ability to target ERK signaling pathways highlights its potential for therapeutic applications in various cancer models.
Product Information
Catalog NumA36755
FormulaC23H22N8O2S
Molecular Weight474.54
CAS Number2890225-50-8
SMILESO=C1C2=C(C3(COC3)N1CC4=NC(C)=CC=C4)SC(C5=C(C)C=NC(NC6=CC=NN6C)=N5)=N2
SynonymsWX001
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