Fig. 1 · Structure

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Sonvuterkib

ERK Inhibitor

Sonvuterkib is a potent inhibitor of extracellular signal-regulated kinases (ERK), demonstrating IC50 values of 1.4 nM for ERK1 and 0.54 nM for ERK2. This orally active compound effectively inhibits cell proliferation, making it a valuable tool in cancer research. Its ability to target ERK signaling pathways highlights its potential for therapeutic applications in various cancer models.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2890225-50-8
Applications ERK Inhibitor
Formula C23H22N8O2S
Molecular Weight 474.54
Synonyms WX001
SMILES
O=C1C2=C(C3(COC3)N1CC4=NC(C)=CC=C4)SC(C5=C(C)C=NC(NC6=CC=NN6C)=N5)=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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