Fig. 1 · Structure
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Sorbitol dehydrogenase-IN-1
Sorbitol Dehydrogenase Inhibitor
Sorbitol dehydrogenase-IN-1 is a potent inhibitor of sorbitol dehydrogenase, exhibiting IC50 values of 4.5 nM for rat and 4 nM for human enzymes. This compound selectively targets sorbitol dehydrogenase, an enzyme involved in the metabolism of sorbitol and glucose, which plays a critical role in various physiological processes. Its inhibitory action makes it a valuable tool for research into diabetic complications and oxidative stress-related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 300551-49-9 |
| Applications | Sorbitol Dehydrogenase Inhibitor |
| Formula | C17H25N7O |
| Molecular Weight | 343.43 |
| SMILES | O[C@@H](C1=NC(N2[C@H](C)CN(C[C@@H]2C)C3=NC(C)=NC(C)=N3)=CC=N1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.