Fig. 1 · Structure

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SORT-PGRN interaction inhibitor 2

SORT-PGRN Interaction Inhibitor

SORT-PGRN Interaction Inhibitor 2 is a selective inhibitor of the SORT-PGRN interaction, targeting the SORT1 protein. This compound has been shown to decrease SORT1 protein expression while enhancing the secretion of extracellular progranulin (PGRN) in mammalian cell lines. It serves as a valuable tool for research in neurological diseases, facilitating studies on the implications of the SORT-PGRN pathway in neurodegenerative disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1008233-79-1
Applications SORT-PGRN Interaction Inhibitor
Formula C19H31NO
Molecular Weight 289.46
SMILES
CC1CN(CCOC2=CC(C)=CC=C2C(C)(C)C)CCC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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