SOS1 activator 2

Catalog No.: A36714
SOS1 Activator
SOS1 Activator 2 engages the SOS1 protein, functioning as a potent activator with a binding affinity characterized by a Kd of 9 nM. By modulating the Ras-ERK signaling pathway, SOS1 Activator 2 serves as a valuable tool in cancer research, facilitating investigations into signal transduction mechanisms and potential therapeutic strategies. Its specificity and efficacy make it an essential reagent for studies aimed at understanding the complexities of oncogenic signaling pathways.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSOS1 Activator 2 engages the SOS1 protein, functioning as a potent activator with a binding affinity characterized by a Kd of 9 nM. By modulating the Ras-ERK signaling pathway, SOS1 Activator 2 serves as a valuable tool in cancer research, facilitating investigations into signal transduction mechanisms and potential therapeutic strategies. Its specificity and efficacy make it an essential reagent for studies aimed at understanding the complexities of oncogenic signaling pathways.
Product Information
Catalog NumA36714
FormulaC26H28ClFN6
Molecular Weight478.99
CAS Number2245237-54-9
SMILESFC1=C(C)C=C(CN2C3=C(N=C2N4CC5(C4)CNC5)C(C6=C(C)NN=C6C)=CC(Cl)=C3)C=C1C
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