SOS1-IN-16

Catalog No.: A63629
SOS1 Inhibitor
SOS1-IN-16 is a selective inhibitor of the SOS1 protein with an IC50 of 7.2 nM, making it a potent tool for studying SOS1-mediated signaling pathways. This compound exhibits inhibitory activity towards CYP3A4 when testosterone is utilized as a substrate, with an IC50 of 8.9 μM. SOS1-IN-16 is primarily applied in cancer research, facilitating the investigation of therapeutic strategies targeting SOS1-related oncogenic processes.
Grouped product items
Size Price Stock Qty
25mg
$1,530.00
In stock
50mg
$1,950.00
In stock
100mg
$2,480.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSOS1-IN-16 is a selective inhibitor of the SOS1 protein with an IC50 of 7.2 nM, making it a potent tool for studying SOS1-mediated signaling pathways. This compound exhibits inhibitory activity towards CYP3A4 when testosterone is utilized as a substrate, with an IC50 of 8.9 μM. SOS1-IN-16 is primarily applied in cancer research, facilitating the investigation of therapeutic strategies targeting SOS1-related oncogenic processes.
Product Information
Catalog NumA63629
FormulaC30H31F3N4O3
Molecular Weight552.59
CAS Number2930763-85-0
SMILESC[C@H](C1=C(C(C(F)(F)CO)=CC=C1)F)NC2=NC(C)=NC3=C2C=C(C4=CC(CC(N(C)C)=O)=C(C=C4)OC)C=C3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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