SOS1-IN-22 is a selective inhibitor of the son of sevenless homolog 1 (SOS1), crucial for the formation of the KRAS-G12C/SOS1 complex with an IC50 value of 40.28 nM. This compound effectively reduces ERK phosphorylation levels, influencing downstream signaling pathways. SOS1-IN-22 is intended for research applications in cancer biology, particularly relevant to pancreatic carcinoma and appendiceal carcinoma.
SOS1-IN-22 is a selective inhibitor of the son of sevenless homolog 1 (SOS1), crucial for the formation of the KRAS-G12C/SOS1 complex with an IC50 value of 40.28 nM. This compound effectively reduces ERK phosphorylation levels, influencing downstream signaling pathways. SOS1-IN-22 is intended for research applications in cancer biology, particularly relevant to pancreatic carcinoma and appendiceal carcinoma.
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